Integration model: MOFA
Dependent variable: diagnosis
Sense check variable: PHF1
Clinical covariates: PHF1, amyloid, pTau, AD,
Braak
Weights threshold: 0.2
Correlation threshold: 0.4
Disease ID (Open target database): MONDO_0004975
The interpretation depends on the direction of the analysis. If the direction is negative, features with positive weights are ‘down regulated’ in samples in disease state.
Direction of the analysis: -1
Factor most strongly correlated with sense check variable selected for downstream analysis: 6
## Trained MOFA with the following characteristics:
## Number of views: 2
## Views names: mRNA proteins
## Number of features (per view): 2945 2945
## Number of groups: 1
## Groups names: group1
## Number of samples (per group): 40
## Number of factors: 15
Names of features that are represented in both transcriptomics and proteomics have either ’_mRNA’ or ’_proteins’ append to their name. Features with orginal names are only seen in a single dataset.
Names of features that are represented in both transcriptomics and proteomics have either ’_mRNA’ or ’_proteins’ append to their name. Features with orginal names are only seen in a single dataset.
## $`1`
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## $`2`
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## $`3`
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## $`4`
## $`1`
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## $`2`
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## $`3`
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## $`4`
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## $`5`
## $`1`
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## $`2`
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## $`3`
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## $`4`
## $`1`
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## $`2`
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## $`3`
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## $`4`
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## $`5`
## No significant TF - gene target enrichment detected!
## Pseudotime analysis was not conducted
Omix v1.0.0 – 2023-06-30 15:51:43
A report by Omix