Vertical integration with SMBPLS

Vertical integration with SMBPLS

integrate_with_sMBPLS(
  multimodal_omics,
  Y,
  design,
  ncomp,
  list.keepX = list(mRNA = c(50), proteins = c(50))
)

Arguments

multimodal_omics

multimodal_object generated by get_multimodal_object

Y

Outcome variable

design

Available values are cor, full, avg. Possible designs for integration are cor(strength of correlation between PC1 of omics layers) or full (The strength of all relationships between dataframes is maximised (= 1) – a “fully connected” design)

ncomp

Number of components

list.keepX

grid of keepX values to keep in the tuning phase

Value

a list object with multimodal_object and model slots

See also

Other Multi-omic integration: getClustNum(), integrate_with_DIABLO(), integrate_with_MBPLS(), integrate_with_MEFISTO(), integrate_with_MOFA(), integrate_with_iCluster(), vertical_integration()