Retrieves posterior probabilities from iCluster integration

Retrieves posterior probabilities from iCluster integration

posterior_probability(
  integrated_object,
  multimodal,
  metadata,
  threshold = 0.9,
  sense_check_variable = NULL
)

Arguments

integrated_object

metadata in multiassay@metadata$integration$iCluster

multimodal

metadata in multiassay@metadata$mulitmodal_object$omics

metadata

metadata in multiassay@metadata$mulitmodal_object$metadata

threshold

Absolute threshold to filter weights

sense_check_variable

default to NULL. High weights should coincide with stronger correlation if the sense_check_variable is an important driver of variation in the designated factor. Will be used to generate a plot if set to a covariate.

Value

List with positive and negative weights above and below the specified threshold, distirbution plots of the weights, and dataframes of the weights for each omic layer.

See also

Other Multi-omic integration downstream analysis: OpenTarget_dataframe(), Transcription_Factor_enrichment_supervised(), Transcription_Factor_enrichment(), circos_TF(), clustering_DE_analysis(), extract_loadings(), extract_multiomic_signature(), extract_weigths(), integrative_results_clustering(), integrative_results_sparse_supervised(), integrative_results_supervised(), integrative_results_unsupervised(), multiomics_modules(), multiomics_network_matrix(), multiomics_network(), plot_module_trajectory(), pseudotime_inference(), sign_signature()